An Efficient Route to Novel Uracil-Based Drug-Like Molecules was written by Babkov, Denis A.;Chizhov, Alexander O.;Khandazhinskaya, Anastasia L.;Corona, Angela;Esposito, Francesca;Tramontano, Enzo;Seley-Radtke, Katherine L.;Novikov, Mikhail S.. And the article was included in Synthesis in 2015.SDS of cas: 1711-11-1 This article mentions the following:
In order to identify new antiretroviral agents, a series of novel uracil derivatives have been synthesized (e.g., I). Optimized conditions for coupling of Weinreb amides with aromatic Grignard reagents allow the convenient preparation of key benzophenone intermediates in high yields and purities. The use of a modified silyl Hilbert-Johnson reaction affords the target compounds under mild conditions. In the experiment, the researchers used many compounds, for example, 3-Cyanobenzoyl chloride (cas: 1711-11-1SDS of cas: 1711-11-1).
3-Cyanobenzoyl chloride (cas: 1711-11-1) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.SDS of cas: 1711-11-1
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics