Lourenco, Nuno M. T. published the artcileIonic Acylating Agents for the Enzymatic Resolution of sec-Alcohols in Ionic Liquids, Related Products of chlorides-buliding-blocks, the publication is European Journal of Organic Chemistry (2010), 6938-6943, S6938/1-S6938/52, database is CAplus.
Potential acylating agents containing pendant ionic groups have been screened for the enzymic kinetic resolution of rac-secondary alcs. in ionic liquids with CAL-B as biocatalyst. This study has allowed the identification of the 1-methyl-3-alkylimidazolium cation attached to a carboxylate group through a C10-alkyl chain as an efficient acylating agent for this transformation. This strategy was applied to the resolution of 2-hydroxycyclohexanecarbonitrile in which the 1R,2S enantiomer was isolated in 35 % ee (73 % yield) and the 1S,2R enantiomer in 97 % ee (23 % yield).
European Journal of Organic Chemistry published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C7H16ClNO2, Related Products of chlorides-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics