Fukuda, Takashi’s team published research in Journal of Natural Products in 82 | CAS: 42074-68-0

Journal of Natural Products published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, HPLC of Formula: 42074-68-0.

Fukuda, Takashi published the artcileNectriatide, a potentiator of amphotericin B activity from Nectriaceae sp. BF-0114, HPLC of Formula: 42074-68-0, the publication is Journal of Natural Products (2019), 82(10), 2673-2681, database is CAplus and MEDLINE.

A new compound, designated nectriatide (1), was isolated as a potentiator of amphotericin B (AmB) activity against Candida albicans from the culture broth of Nectriaceae sp. BF-0114. This structure was elucidated based on spectroscopic analyses (1D and 2D NMR data), chem. methods, and total synthesis. Compound 1 was a unique cyclotetrapeptide consisting of L-N-methyltyrosine, anthranilic acid, L-alanine, and L-valine. Compound 1 and several synthetic derivatives, including linear peptides, potentiated AmB activity against C. albicans by up to 16-fold (the MIC value of AmB decreased from 0.5μg/mL to 0.031μg/mL in combination with test compound).

Journal of Natural Products published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, HPLC of Formula: 42074-68-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics