Singh, Rahul published the artcileSynthesis and exploration of configurational dynamics in equilibrating E/Z 2-aryliminothiazolidin-4-ones using NMR and estimation of thermodynamic parameters, Safety of 1-(4-Chlorophenyl)thiourea, the publication is New Journal of Chemistry (2022), 46(11), 5012-5025, database is CAplus.
In the present study, 2-aryliminothiazolidin-4-ones I [R1 = H, OMe, NMe2, NO2; R2 = H, Me, MeO, Cl, NO2] were utilized as dynamic chem. systems, whose different states were modulated in a reversible fashion through specific chem. stimuli. The in-depth NMR investigation revealed that the magnitude of rotational energy barrier ÎGâ?/sup> was affected markedly by (1) the solvent polarity; (2) the electronic nature of the ring system present on the exocyclic CQN bond and (3) the temperature of the system. The derivatives of I exist in two isomeric forms at room temperature in DMSO-d6: (2E,5Z,7E) (2Z,5Z,7E). The stereodynamics of the synthesized derivatives I were investigated using variable temperature dynamic 1H-NMR (VT DNMR). The ÎGâ?/sup> values (â?5 kcal mol-1) estimated for the dynamic process depicted a significant barrier between two forms in solution at ambient temperature To go a step further, line shape anal. were also performed to get a clear understanding of the equilibration mechanism.
New Journal of Chemistry published new progress about 3696-23-9. 3696-23-9 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Thiourea,Amine,Benzene,Amide, name is 1-(4-Chlorophenyl)thiourea, and the molecular formula is C17H16O2, Safety of 1-(4-Chlorophenyl)thiourea.
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