Ma, Zhihua published the artcileDiscovery of the imidazole-derived GPR40 agonist AM-3189, COA of Formula: C7H8BClO2, the publication is Bioorganic & Medicinal Chemistry Letters (2016), 26(1), 15-20, database is CAplus and MEDLINE.
As a follow-up to the GPR40 agonist AMG 837, which was evaluated in clin. trials for the treatment of type II diabetes, further optimization led to the discovery of AM-3189 I. I is representative of a new class of compounds with minimal CNS penetration, superior pharmacokinetic properties and in vivo efficacy comparable to AMG 837.
Bioorganic & Medicinal Chemistry Letters published new progress about 209919-30-2. 209919-30-2 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Boronic Acids,Boronic acid and ester, name is 4-Chloro-2-methylphenylboronic acid, and the molecular formula is C7H8BClO2, COA of Formula: C7H8BClO2.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics