Djud, Mateja published the artcileSynthesis of monosubstituted thioureas by vapour digestion and mechanochemical amination of thiocarbamoyl benzotriazoles, Recommanded Product: 1-(4-Chlorophenyl)thiourea, the publication is Green Chemistry (2016), 18(9), 2666-2674, database is CAplus.
Thiocarbamoyl benzotriazoles, as safe and easy-to-handle isothiocyanate equivalent, were quant. converted to N-monosubstituted thioureas by vapor digestion synthesis under an ammonia atm. This simple, but timely process provided a synthetic platform that enabled the “slow” amination reaction to be successfully transformed into a rapid one aided by mechanochem. milling. The ammonium chloride/sodium carbonate equimolar mixture allowed in situ formation of ammonia under ball-milling conditions. This novel and green approach yielded aromatic and aliphatic primary thioureas in near-quant. isolated yields with workup entirely based on using only water. In addition, the mol. and crystal structures of selected polyaromatic primary thioureas were determined from the synchrotron powder diffraction data.
Green Chemistry published new progress about 3696-23-9. 3696-23-9 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Thiourea,Amine,Benzene,Amide, name is 1-(4-Chlorophenyl)thiourea, and the molecular formula is C7H7ClN2S, Recommanded Product: 1-(4-Chlorophenyl)thiourea.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics