Oh, Sangmi published the artcileConstruction of a Polyheterocyclic Benzopyran Library with Diverse Core Skeletons through Diversity-Oriented Synthesis Pathway, Formula: C7H8BClO2, the publication is Journal of Combinatorial Chemistry (2010), 12(4), 548-558, database is CAplus and MEDLINE.
In this study, a divergent and practical solid-phase parallel diversity-oriented synthesis (DOS) strategy was successfully applied for the construction of five discrete core skeletons embedded with privileged benzopyranyl (chroman/2H-chromene) substructure. The diversity of these core skeletons was expanded through the introduction of various substituents at the benzopyran aromatic and 2 positions and at the N atoms of appended heterocycles from a single key intermediate in five different pathways. More importantly, we efficiently maximized the mol. diversity through the transformation of the core skeleton itself by using the library-to-library concept and created a distinctively different collection of small mols. with the same building blocks. A 434-member polyheterocyclic benzopyran library was constructed on a scale of about 10 mg with the potential for further diversification. Without further purification, the average purity of the library is 85%.
Journal of Combinatorial Chemistry published new progress about 209919-30-2. 209919-30-2 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Boronic Acids,Boronic acid and ester, name is 4-Chloro-2-methylphenylboronic acid, and the molecular formula is C7H8BClO2, Formula: C7H8BClO2.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics