Liang, Shuaishuai’s team published research in Organic Letters in 20 | CAS: 10543-42-7

Organic Letters published new progress about 10543-42-7. 10543-42-7 belongs to chlorides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Chloride,Sulfonyl chlorides,Ester, name is Coumarin-6-sulfonyl chloride, and the molecular formula is C9H5ClO4S, Recommanded Product: Coumarin-6-sulfonyl chloride.

Liang, Shuaishuai published the artcileCopper-Catalyzed Vicinal Chloro-thiolation of Alkynes with Sulfonyl Chlorides, Recommanded Product: Coumarin-6-sulfonyl chloride, the publication is Organic Letters (2018), 20(22), 7024-7028, database is CAplus and MEDLINE.

In the presence of CuCl, terminal and internal aryl and alkyl alkynes such as RCCH (R = 4-MeC6H4, Ph, 4-BuC6H4, 4-PhC6H4, 4-ClC6H4, 4-BrC6H4, 4-F3CC6H4, 4-NCC6H4, 4-O2NC6H4, 4-MeO2CC6H4, 3-pyridinyl, PhCH2, PhOCH2, PhCH2NMeCH2, 1,3-dioxo-2-isoindolylmethyl, BrCH2, ClCH2CH2CH2) underwent regioselective and diastereoselective chlorothiolation with sulfonyl chlorides such as phenylsulfonyl chloride mediated by Ph3P in DMF to yield (E)-chloroalkenyl thioethers such as (E)-RC(SPh):CHCl. The mechanism of the reaction was studied; evidence was obtained for thiyl radical intermediates, while DFT calculations of the intermediate chloroalkenyl copper complexes rationalized the observed regioselectivity.

Organic Letters published new progress about 10543-42-7. 10543-42-7 belongs to chlorides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Chloride,Sulfonyl chlorides,Ester, name is Coumarin-6-sulfonyl chloride, and the molecular formula is C9H5ClO4S, Recommanded Product: Coumarin-6-sulfonyl chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics