Lee, Koo published the artcileFluorobenzamidrazone thrombin inhibitors: influence of fluorine on enhancing oral absorption, Application In Synthesis of 61551-49-3, the publication is Bioorganic & Medicinal Chemistry Letters (1999), 9(17), 2483-2486, database is CAplus and MEDLINE.
LB30057 (I, R = H) is a selective and efficacious oral thrombin inhibitor. Fluorine-substitution on the phenylene ring of the benzamidrazone portion in both compound I (R = H) and its derivatives gave, in many cases, enhanced oral absorption in rats while maintaining the intrinsic potency and selectivity. Compound I (R = F) demonstrated a 3-fold increase in absorption.
Bioorganic & Medicinal Chemistry Letters published new progress about 61551-49-3. 61551-49-3 belongs to chlorides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 5,6,7,8-Tetrahydronaphthalene-2-sulfonyl chloride, and the molecular formula is C10H11ClO2S, Application In Synthesis of 61551-49-3.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics