Kikuchi, Haruhisa published the artcileIsolation of a Cyclic Depsipeptide, Aspergillicin F, and Synthesis of Aspergillicins with Innate Immune-Modulating Activity, Safety of 2-Chlorotrityl chloride, the publication is Journal of Natural Products (2015), 78(8), 1949-1956, database is CAplus and MEDLINE.
Innate immunity is the front line of self-defense against microbial infection. After searching for natural compounds that regulate innate immunity using an ex vivo Drosophila culture system, we identified a new cyclic depsipeptide, aspergillicin F, from the fungus Aspergillus sp., as an innate immune suppressor. The total synthesis and biol. evaluation of the aspergillicin family, including aspergillicin F, were performed, revealing that slight structural differences in the side chains of amino acid residues alter innate immunity-regulating activity.
Journal of Natural Products published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, Safety of 2-Chlorotrityl chloride.
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Chlorides – an overview | ScienceDirect Topics