Gold(I)-Catalyzed 1,4-and/or 1,5-Heteroaryl Migration Reactions through Regiocontrolled Cyclizations was written by Wang, Chengyu;Xie, Xin;Liu, Jun;Liu, Yuanhong;Li, Yuxue. And the article was included in Chemistry – A European Journal in 2015.Name: 5-Chloro-2-(phenylethynyl)benzaldehyde The following contents are mentioned in the article:
Gold(I)-catalyzed regioselective cycloisomerizations of furan-ynes were described. The reaction provided a concise access to stereodefined trisubstituted alkenes by endo cyclization with concomitant 1,5-migration of the furanyl group in the presence of unactivated 3° mol. sieves. In the absence of mol. sieves, indene products were generated by exo cyclization, followed by 1,4-furanyl migration/cyclization. The scope for 1,5-migrations was extended to other heterocycles, such as benzofurans, thiophenes and pyrroles. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Name: 5-Chloro-2-(phenylethynyl)benzaldehyde).
5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Name: 5-Chloro-2-(phenylethynyl)benzaldehyde
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics