Nucleophilic aromatic substitution in heterocycles: alcoholysis and hydrolysis of 2-anilino-4,6-dichloro-1,3,5-triazines was written by Renfrew, A. Hunter M.;Taylor, John A.;Whitmore, James M. J.;Williams, Andrew. And the article was included in Journal of the Chemical Society in 1994.Recommanded Product: 2272-40-4 The following contents are mentioned in the article:
Kinetics are reported for the alk. hydrolysis and alcoholysis of the title compounds A rate law and linear Hammett and Broensted relations are obtained. The data are consistent with a mechanism involving addition of the hydroxide ion to the neutral triazine. The polar substituent effects on the hydroxide ion reactivity indicate that there is substantial charge accumulation in the triazine nucleus in the transition state of the addition step. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Recommanded Product: 2272-40-4).
4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Recommanded Product: 2272-40-4
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics