Synthesis and antibacterial activity of 2-phenyl amino-4-(aryl thio ureido/aryl ureido)-6-[{4′-(2”,4”-dichloro-5”-fluoro phenyl)-6′-(3”,4”,5”-trimethoxy phenyl) pyrimidine-2′-yl}amino]-s-triazine was written by Patel, Vikram;Desai, Vikas. And the article was included in Asian Journal of Chemistry in 2003.Quality Control of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine The following contents are mentioned in the article:
Some new s-triazine derivatives have been prepared by the condensation of aniline and cyanuric chloride giving 2-Ph amino-4,6-dichloro-s-triazine, which on reaction with aryl thio ureido/aryl ureido gives 2-Ph amino-4-aryl thio ureido/aryl ureido-6-chloro-s-triazine which on further reaction with 2-amino-4-(2′,4′-dichloro-5′-fluoro phenyl)-6-(3′,4′,5′-trimethoxy phenyl) pyrimidine gives the title compound The structure of the product has been characterized by elemental anal. and spectral data. The products have been screened for their antibacterial activity against Staphylococcus aureus and Escherichia coli. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Quality Control of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine).
4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Quality Control of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics