Gold-Catalyzed One-Pot A3-Coupling/1,5-Hydride Shift/Schmittel-Type Cyclization: From Aldehydes, Amines and Alkynes to the Synthesis of Benzo[b]fluorenes was written by Lustosa, Danilo M.;Hartmann, Deborah;Rudolph, Matthias;Rominger, Frank;Hashmi, A. Stephen K.. And the article was included in European Journal of Organic Chemistry in 2020.Related Products of 1186603-47-3 The following contents are mentioned in the article:
A step-economic gold-catalyzed one-pot synthesis of benzo[b]fluorenes was described from aldehydes, alkynes and amines via an A3-coupling/1,5-hydride shift/Schmittel-type cyclization. The formation of the allene intermediate was not dependent on a previous installation of reaction triggers and upon cyclization delivered benzo[b]fluorenes. With this method, just by an easy modification of the starting materials in a modular way, nineteen benzo[b]fluorenes bearing different substituents Ar1, Ar2 and Ar3, were prepared Overall, three new carbon-carbon bonds were formed in one-pot. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Related Products of 1186603-47-3).
5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Related Products of 1186603-47-3
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics