Preparation of some 2-(arylamino)-4-[3-(2-methylphenyl)thiazolidine-2,4-dion-5-ylamino]-6-isonicotinylhydrazino-s-triazines as antibacterial and antituberculostatic agents was written by Desai, N. C.;Shukla, H. K.;Thaker, K. A.. And the article was included in Journal of the Institution of Chemists (India) in 1984.Reference of 2272-40-4 The following contents are mentioned in the article:
Treating arylaminotriazines I [R = (un)substituted Ph, PhCH2) with 5-amino-3-(2-methylphenyl)-2,4-thiazolidinedione in Me2CO at 35-40° gave II which were further treated with isoniazid to give III. The latter were effective against Mycobacterium tuberculosis at 0.02 mg/mL and against Staphylococcus aureus and Escherichia coli (no data). This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Reference of 2272-40-4).
4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Reference of 2272-40-4
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics