Mistry, Nisha published the artcileCatalytic asymmetric synthesis of geminal-dicarboxylates, Related Products of chlorides-buliding-blocks, the publication is Chemical Science (2018), 9(29), 6307-6312, database is CAplus and MEDLINE.
Stereogenic acetals, spiroacetals and ketals are well-studied stereochem. features that bear two heteroatoms at a common carbon atom. These stereocenters are normally found in cyclic structures while linear (or acyclic) analogs bearing two heteroatoms are rare. Chiral geminal-dicarboxylates are illustrative, there is no current way to access this class of compounds while controlling the stereochem. at the carbon center bound to two oxygen atoms. Here, a rhodium-catalyzed asym. carboxylation of ester-containing allylic bromides to form stereogenic carbon centers bearing two different carboxylates with high yields and enantioselectivities is reported. The products, which are surprisingly stable to a variety of acidic and basic conditions, can be manipulated with no loss of enantiomeric purity as demonstrated by ring closing metathesis reactions to form chiral lactones, which have been extensively used as building blocks in asym. synthesis.
Chemical Science published new progress about 6313-54-8. 6313-54-8 belongs to chlorides-buliding-blocks, auxiliary class Pyridine,Chloride,Carboxylic acid, name is 2-Chloroisonicotinic acid, and the molecular formula is C6H4ClNO2, Related Products of chlorides-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics