Boyer, John-Christopher published the artcilePhotomodulation of Fluorescent Upconverting Nanoparticle Markers in Live Organisms by Using Molecular Switches, Computed Properties of 219537-97-0, the publication is Chemistry – A European Journal (2012), 18(11), 3122-3126, S3122/1-S3122/17, database is CAplus and MEDLINE.
It is successfully demonstrated that the ability to modulate the luminescence from upconverting nanoparticles in vitro and in vivo by taking advantage of the well-understood photochem. of DTE mol. switches decorated onto nanoparticle surfaces by the use of CuACC chem. By reversibly converting the photoswitch back and forth between the two isomers by using UV and visible light, we are able to toggle the system between on (bright fluorescence) and off (quenched fluorescence) states. This process can be cycled multiple times before any degradation of the nanoparticles or the photo-switch renders the system impractical. The system has an advantage over ‘caged’ fluorophores as the luminescence of our designed nanoparticles can be repeatedly cycled through on and off states. Systems such as the one described not only have the capacity to reversibly control the intensity of the probe emission, through selective absorption, they can also alter the color of the emitted light from multicolored probes; this further enhances the imaging capabilities.
Chemistry – A European Journal published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Computed Properties of 219537-97-0.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics