Synthesis of thienyl-substituted isochromene derivatives through gold-catalyzed tandem heteroarylation/cycloisomerization of ortho-alkynylbenzaldehydes with thiophenes was written by Zhu, Hongbo;Meng, Xin;Cao, Ziping;Chen, Guang;Sun, Xuejun;You, Jinmao. And the article was included in Synthetic Communications in 2017.Electric Literature of C15H9ClO The following contents are mentioned in the article:
A gold-catalyzed tandem heteroarylation/cycloisomerization reaction of ortho-alkynylbenzaldehydes with thiophenes was described. By this reaction, a variety of 1-(thiophen-2-yl)-1H-isochromene derivatives were obtained in good yield. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Electric Literature of C15H9ClO).
5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Electric Literature of C15H9ClO
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics