Luo, Mengqiang et al. published their research in Journal of the Iranian Chemical Society in 2021 | CAS: 75-57-0

Tetramethylammonium chloride (cas: 75-57-0) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Product Details of 75-57-0

One-pot synthesis of sulfonylhydrazones from sulfonyl chloride, hydrazine hydrate and vinyl azide in water was written by Luo, Mengqiang;Wang, Hai;Ren, Xiaorong;Lu, Ruijuan;Qi, Chenze;Zhang, Yaohong;Shen, Runpu. And the article was included in Journal of the Iranian Chemical Society in 2021.Product Details of 75-57-0 The following contents are mentioned in the article:

A facile and eco-friendly protocol for the synthesis of sulfonylhydrazones I [R = Ph, 4-MeC6H4, 4-FC6H4, 4-ClC6H4, 4-BrC6H4; R1 = Me, Ph, 4-MeOC6H4, etc.] from sulfonyl chlorides, hydrazine hydrate and vinyl azides was developed. The unique advantage of this approach was that desired products could be obtained efficiently in water, which meets the requirements of green chem. and provided good perspectives for the sustainable production of new drug candidate. Also, this reaction proceeded in moderate to good yields with a wide tolerance of functional groups. This study involved multiple reactions and reactants, such as Tetramethylammonium chloride (cas: 75-57-0Product Details of 75-57-0).

Tetramethylammonium chloride (cas: 75-57-0) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Product Details of 75-57-0

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Schmidt, Nina G. et al. published their research in Angewandte Chemie, International Edition in 2017 | CAS: 95-88-5

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Recommanded Product: 4-Chlororesorcinol

Biocatalytic Friedel-Crafts Acylation and Fries Reaction was written by Schmidt, Nina G.;Pavkov-Keller, Tea;Richter, Nina;Wiltschi, Birgit;Gruber, Karl;Kroutil, Wolfgang. And the article was included in Angewandte Chemie, International Edition in 2017.Recommanded Product: 4-Chlororesorcinol The following contents are mentioned in the article:

The Friedel-Crafts acylation is commonly used for the synthesis of aryl ketones, and a biocatalytic version, which may benefit from the chemo- and regioselectivity of enzymes, has not yet been introduced. Described here is a bacterial acyltransferase which can catalyze Friedel-Crafts C-acylation of phenolic substrates in buffer without the need of CoA-activated reagents. Conversions reach up to >99 %, and various C- or O-acyl donors, such as DAPG or isopropenyl acetate, are accepted by this enzyme. Furthermore the enzyme enables a Fries-like rearrangement reaction of resorcinol derivatives These findings open an avenue for the development of alternative and selective C-C bond formation methods. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Recommanded Product: 4-Chlororesorcinol).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Recommanded Product: 4-Chlororesorcinol

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Ostrovskii, Vladimir A. et al. published their research in Chemistry of Heterocyclic Compounds in 2021 | CAS: 638-07-3

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.COA of Formula: C6H9ClO3

Synthesis and antiviral activity of nonannulated tetrazolylpyrimidines was written by Ostrovskii, Vladimir A.;Danagulyan, Gevorg G.;Nesterova, Olga M.;Pavlyukova, Yulia N.;Tolstyakov, Vladimir V.;Zarubina, Olga S.;Slepukhin, Pavel A.;Esaulkova, Yana L.;Muryleva, Anna A.;Zarubaev, Vladimir V.;Trifonov, Rostislav E.. And the article was included in Chemistry of Heterocyclic Compounds in 2021.COA of Formula: C6H9ClO3 The following contents are mentioned in the article:

Nonannulated tetrazolylpyrimidines in the structure of which the heterocyclic fragments were separated by hydrazinocarbonylmethyl I [R = H, Me], methylpyrazolyl II, groups or a sulfur atom III [R1 = Ph; R2 = H; R1 = CH2CO2H, R2 = Me] were synthesized. Some of these compounds showed moderate in vitro activity against H1N1 subtype of influenza A virus. The selectivity index of the anti-influenza action of {5-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-1H-tetrazol-1-yl}acetic acid, which had very low cytotoxicity, was twice as high as the selectivity index of the reference drug rimantadine. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3COA of Formula: C6H9ClO3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.COA of Formula: C6H9ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Kavitha, Kotthireddy et al. published their research in Molecular Diversity in 2019 | CAS: 638-07-3

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Category: chlorides-buliding-blocks

An unusual synthesis of 3-(2-(arylamino)thiazol-4-yl)-2H-chromen-2-ones from ethyl 2-(chloromethyl)-2-hydroxy-2H-chromene-3-carboxylate via benzopyran ring opening was written by Kavitha, Kotthireddy;Srikrishna, Devulapally;Sridhar, Balasubramanian;Aparna, Pasula. And the article was included in Molecular Diversity in 2019.Category: chlorides-buliding-blocks The following contents are mentioned in the article:

An unusual and unexpected synthesis of 3-(2-(arylamino)thiazol-4-yl)-2H-chromen-2-ones was observed by the reaction of Et 2-(chloromethyl)-2-hydroxy-2H-chromene-3-carboxylate with various arylthioureas in ethanol under mild reaction conditions with excellent yields. The ambiguity in the structure of the obtained products was solved by recording its single-crystal X-ray anal. This protocol was found to be a novel approach for the preparation of title compounds via benzopyran ring opening. A systematic plausible mechanism was proposed for the formation of the product. Also, an efficient one-pot three-component method was demonstrated for the formation of title compounds starting from salicylaldehyde. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Category: chlorides-buliding-blocks).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Fernandez-Navarro, Leticia et al. published their research in Inorganic Chemistry in 2021 | CAS: 75-57-0

Tetramethylammonium chloride (cas: 75-57-0) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Electric Literature of C4H12ClN

Isolation of the Elusive Heptavanadate Anion with Trisalkoxide Ligands was written by Fernandez-Navarro, Leticia;Nunes-Collado, Aitor;Artetxe, Benat;Ruiz-Bilbao, Estibaliz;San Felices, Leire;Reinoso, Santiago;San Jose Wery, Ana;Gutierrez-Zorrilla, Juan M.. And the article was included in Inorganic Chemistry in 2021.Electric Literature of C4H12ClN The following contents are mentioned in the article:

The unprecedented heptavanadate cluster has been isolated from reactions between trisalkoxide ligands and vanadate in water at pH = 2 as a series of alkylammonium [HxV7O18(H2O)((OCH2)3CR)](4-x)- salts (13, R = CH2OH; 4, R = CH3). Their structures have been determined and the partial stability of 4 in water assessed by a combination of multinuclear NMR spectroscopy and ESI-MS. The heptavanadate unit reported herein could represent an intermediate species in the formation of decavanadate that is blocked by attachment of tripodal ligands. This study involved multiple reactions and reactants, such as Tetramethylammonium chloride (cas: 75-57-0Electric Literature of C4H12ClN).

Tetramethylammonium chloride (cas: 75-57-0) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Electric Literature of C4H12ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Desai, K. R. et al. published their research in Journal of the Indian Chemical Society in 1985 | CAS: 2272-40-4

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.SDS of cas: 2272-40-4

Synthesis and antibacterial activity of 2-(2-carbamoylphenoxy)-4-anilino-6-phenylureido-s-triazines was written by Desai, K. R.;Pathak, M. M.. And the article was included in Journal of the Indian Chemical Society in 1985.SDS of cas: 2272-40-4 The following contents are mentioned in the article:

Title compounds I (R = H, o-Me, m-Me, p-Me, p-NO2, p-Cl, etc.) were prepared in 69-82% yield by treating the chlorotriazine II with RC6H4NHCONH2 and aqueous NaOH in Me2CO or dioxane. By the cup-plate method I (R = H) and I (R = o-Me) showed zones of inhibition against Staphylococcus aureus of 2.5 and 2 mm resp. By the same method against Escherichia coli, I (R = m-Me) and I (R = p-NO2) showed zones of inhibition of 3 and 2 mm resp. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4SDS of cas: 2272-40-4).

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.SDS of cas: 2272-40-4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Leicht, Hannes et al. published their research in Journal of the American Chemical Society in 2017 | CAS: 6294-17-3

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Electric Literature of C6H12BrCl

Synergetic Effect of Monomer Functional Group Coordination in Catalytic Insertion Polymerization was written by Leicht, Hannes;Goettker-Schnetmann, Inigo;Mecking, Stefan. And the article was included in Journal of the American Chemical Society in 2017.Electric Literature of C6H12BrCl The following contents are mentioned in the article:

PhS- and PhNH-functionalized dienes are copolymerized efficiently with butadiene to stereoregular copolymers by [(mesitylene)Ni(allyl)][BArF4] (Ni-1). Overall polymerization rates and comonomer incorporations depend strongly on the linker length between the diene moiety and functional group, in, e.g., PhS-(CH2)xC(=CH2)-CH=CH2 (PhS-x-BD, x = 3-7), in particular for certain linker lengths high comonomer reactivity ratios stand out. This effect is related to a favorable binding of the comonomer to the active site comprising coordination of its functional group, which significantly enhances comonomer incorporation in the growing polymer chain. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Electric Literature of C6H12BrCl).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Electric Literature of C6H12BrCl

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

De Abreu, Maxime et al. published their research in Organic & Biomolecular Chemistry in 2021 | CAS: 1186603-47-3

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Safety of 5-Chloro-2-(phenylethynyl)benzaldehyde

Silver-catalyzed tandem cycloisomerization/hydroarylation reactions and mechanistic investigations for an efficient access to 1,2-dihydroisoquinolines was written by De Abreu, Maxime;Tang, Yue;Brachet, Etienne;Selkti, Mohamed;Michelet, Veronique;Belmont, Philippe. And the article was included in Organic & Biomolecular Chemistry in 2021.Safety of 5-Chloro-2-(phenylethynyl)benzaldehyde The following contents are mentioned in the article:

An efficient silver-catalyzed tandem reaction for the formation of 1,2-dihydroisoquinoline derivatives is herein reported. Highly functionalized multiheterocyclic scaffolds are accessible in a straightforward manner using readily accessible starting materials under mild conditions. This methodol. offers an attractive route for the synthesis and development of a biol. relevant new heterocyclic pharmacophore, merging the biol. activities of isoquinolines with those of various nitrogen-containing heterocycles (indoles, pyrroles) incorporated during the tandem reaction. Mechanistic investigations were also conducted along with a large scope and limitation study, modifying various sites of this pharmacophore. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Safety of 5-Chloro-2-(phenylethynyl)benzaldehyde).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Safety of 5-Chloro-2-(phenylethynyl)benzaldehyde

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Santoso, Kristiana T. et al. published their research in ChemistrySelect in 2020 | CAS: 638-07-3

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.SDS of cas: 638-07-3

Synthesis of Functionalised Chromonyl-pyrimidines and Their Potential as Antimycobacterial Agents was written by Santoso, Kristiana T.;Brett, Matthew W.;Cheung, Chen-Yi;Cook, Gregory M.;Stocker, Bridget L.;Timmer, Mattie S. M.. And the article was included in ChemistrySelect in 2020.SDS of cas: 638-07-3 The following contents are mentioned in the article:

Herein, the development of chromonyl-pyrimidines I [R1 = Me, CH2Cl, CH2OMe, Ph, 4-FC6H4; R2 = H, C(O)Ph; R3 = CO2H, CO2Et, Ph, 4-NH2C6H4, 4-O2NC6H4] as a new tuberculosis (TB) drug scaffold was presented. A library of chromonyl-pyrimidines was synthesized, from which lead compounds I [R1 = Me, R2 = H, Ph R3 = Ph; R1 = Me, R2 = R3 = Ph] was identified. From this work, the potential of chromonyl-pyrimidines as therapeutics for TB was demonstrated. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3SDS of cas: 638-07-3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.SDS of cas: 638-07-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Yu, Xingxin et al. published their research in Tetrahedron in 2011 | CAS: 1186603-47-3

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Synthetic Route of C15H9ClO

An efficient route to diverse H-pyrazolo[5,1-a]isoquinolines via sequential multi-component/cross-coupling reactions was written by Yu, Xingxin;Pan, Xiaolin;Wu, Jie. And the article was included in Tetrahedron in 2011.Synthetic Route of C15H9ClO The following contents are mentioned in the article:

Multi-component reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, electrophile (bromine or iodine), and ketone or aldehyde under mild conditions proceeds smoothly to afford the functionalized H-pyrazolo[5,1-a]isoquinolines in good yields. E.g., reaction of 2-(PhCC)C6H4CHO, TsNHNH2, butanal, and Br2 gave 45% H-pyrazolo[5,1-a]isoquinoline I. This one-pot process involves intermol. condensation, electrophilic cyclization, nucleophilic addition, intramol. condensation, and aromatization. The resulting halo-containing H-pyrazolo[5,1-a]isoquinolines could be further elaborated via palladium-catalyzed cross-coupling reactions with arylboronic acids. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Synthetic Route of C15H9ClO).

5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Synthetic Route of C15H9ClO

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics