Month: November 2022

On March 19, 2015, Nakamura, Kimie published a patent.Product Details of 4569-86-2 The title of the patent was Corona treated film staining solution and visual evaluation method using the same. And the patent contained the following:

The solution contains a colorant having quaternary ammonium salt structure which had been removed and a solvent which can dissolve a substrate and is incompatible with water such as hexane, CHCl3, toluene and MEK. An example of the colorant is Methylene Violet 3Rax or Janus Green B. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Product Details of 4569-86-2

The Article related to staining agent colona discharge film methylene violet, Coatings, Inks, and Related Products: General and other aspects.Product Details of 4569-86-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On April 22, 1999, Moeller, Hinrich; Meinigke, Bernd published a patent.Recommanded Product: 4569-86-2 The title of the patent was Use of phenazinium salts for dyeing keratin fibers. And the patent contained the following:

Phenazinium salts I [R1, R2 = (alkyl- or aryl-substituted) amino; R3, R6 = H, C1-4 alkyl, (alkyl- or aryl-substituted) amino; R4, R5 = H, C1-4 alkyl; R7 = C1-4 alkyl, aryl; X- = anion] are provided as direct hair dyes which produce excellent brilliance and depth of color with many color nuances. The dyes show excellent fastness with little potential for sensitization. Thus, a hair-dyeing cream containing 0.1 weight% Methylene Violet 3RAX, applied to blond hair for 30 min at 30°, produced a beet-red color. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Recommanded Product: 4569-86-2

The Article related to phenazinium hair dye, Essential Oils and Cosmetics: Hair Preparations and other aspects.Recommanded Product: 4569-86-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On January 31, 2009, Lakshmi, P. Baby Sudha; Vardhan, S. V. M.; Ramachandran, D.; Rambabu, C. published an article.Recommanded Product: 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride The title of the article was Use of some basic dyes in the extractive spectrophotometric determination of tranexamic acid. And the article contained the following:

A simple and sensitive spectrophotometric method is developed for the determination of tranexamic acid. It is based on the formation of colored ion-pair complex between the tranexamic acid and basic dyes (methylene blue, methylene violet, and saframin-O) in the aqueous phase at suitable pH extractable into chloroform showing the characteristic absorption maximum at 650, 550, and 520 nm, resp. The method was applied to pharmaceutical formulations. The method was statistically validated and is found to be precise and accurate. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Recommanded Product: 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

The Article related to tranexamic acid determination basic dye spectrophotometry, Pharmaceutical Analysis: Natural Drug Materials and other aspects.Recommanded Product: 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On April 30, 2022, Hu, Chen; Ye, Baijun; Huang, Zedu; Chen, Fener published an article.COA of Formula: C7H11ClO3 The title of the article was Development of an engineered ketoreductase with improved activity, stereoselectivity and relieved substrate inhibition for enantioselective synthesis of a key (R)-α-lipoic acid precursor. And the article contained the following:

Me (R)-8-chloro-6-hydroxyoctanoate ((R)-MCHO, (R)-2a) is a key precursor that can be utilized in the production of (R)-α-lipoic acid ((R)-LA) of pharmaceutical and dietary significance. Owing to its high atom economy, maximum theor. yield of 100%, and environmentally friendliness, ketoreductase (KRED)-catalyzed stereoselective reduction of Me 8-chloro-6-oxooctanoate (MCOO, 1a), an ε-keto ester, represents an efficient yet challenging approach to the synthesis of (R)-2a. We report herein the development of a versatile KRED, referred to as SsCRL211H/V127A/L135I, through enzyme screening followed by structure-guided protein engineering, which was assisted by comparative anal. of enzyme-/substrate- binding modes in prereaction-state and free-state mol. dynamics (MD) simulations. This enzyme variant displayed 2.8-fold increased kcat (16.77 s-1) towards 1a relative to the wild-type SsCR, improved stereoselectivity (98.0% ee), and no substrate inhibition. Insights were gained on the origin of the enhancement of enzyme’s catalytic activity and stereoselectivity, by conducting complete deconvolution experiments and MD simulations. In the presence of 60 g·L-1 of wet E. coli cells coexpressing SsCRL211H/V127A/L135I and glucose dehydrogenase (GDH), and 0.05 mM NADP+, complete reduction of 260 g·L-1 of 1a was achieved furnishing (R)-2a with 98.0% ee with a space-time yield of 391 g·L-1·d-1, thereby showcasing the promising potential of this ketoreductase in the asym. synthesis of (R)-2a. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).COA of Formula: C7H11ClO3

The Article related to escherichia enantioselective ketoreductase alpha lipoic acid, Fermentation and Bioindustrial Chemistry: Other and other aspects.COA of Formula: C7H11ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On October 31, 2014, Baranek, Wit; Kopyto, Dorota; Hanke, Michal; Wyrebska, Lucja; Sobolewski, Wieslaw published a patent.SDS of cas: 4569-86-2 The title of the patent was Method for producing cathodic copper. And the patent contained the following:

A method of production of cathodic copper using copper anodes in electrolytes containing copper salt (35 – 55 g/dm3), sulfuric acid (150 – 200 g/dm3), nickel ions (0.01 – 0.05 g/dm3) and chlorine (0.01 – 0.05 g/dm3) with addnl. content of impurity ions up to 20 g/dm3 is described. The bath also contained electrodeposition inhibitors such as hexylmethylene-guanidine polymer and/or choline chloride and/or di-Et safranine together with animal glue and thiourea. The composition of the electrorefining copper bath is described in details. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).SDS of cas: 4569-86-2

The Article related to cathodic copper bath composition electrodeposition electroplating, Electrochemistry: Industrial Cathodic Processes and other aspects.SDS of cas: 4569-86-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On May 31, 2018, Zhang, Yun; Wang, Jing; Zhu, Zifang; Ma, Tao; Chen, Luming published a patent.Related Products of 4569-86-2 The title of the patent was Copper crystal particles having highly preferred orientation and preparation method thereof. And the patent contained the following:

An electroplating Cu layer includes bamboo-like Cu crystal particles having a highly preferred orientation. The bamboo-like Cu crystal particles have a long axis direction and a short axis direction, and the bamboo-like Cu crystal particles have a length of 20 nm to 5 μm in the long axis direction and a length of 20 nm to 2 μm in the short axis direction. A method of preparing the bamboo-like Cu crystal particles is also disclosed. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Related Products of 4569-86-2

The Article related to copper crystal particle preferred orientation preparation electrodeposition, Electrochemistry: Industrial Cathodic Processes and other aspects.Related Products of 4569-86-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Dow, Wei-Ping; Li, Chih-Chan; Lin, Meng-Wen; Su, Ging-Wen; Huang, Chen-Chia published an article in 2009, the title of the article was Copper Fill of Microvia Using a Thiol-Modified Cu Seed Layer and Various Levelers.Electric Literature of 4569-86-2 And the article contains the following content:

Microvia filling by Cu electroplating was carried out using a plating bath containing a suppressor and a leveler without an accelerator. The required accelerator was adsorbed onto the Cu seed layer of the microvia in a predipping bath before the filling plating. This pretreatment is similar to the self-assembled monolayer of thiol mols. that forms on a Cu surface. The suppressor was poly(ethylene glycol) (PEG), and 5 levelers, namely, Janus green B, diazine black, methylene violet, safranine O, and Alcian blue, were employed to screen for the best plating formula suitable for a plating process in which no accelerator was present in the plating solution The thiol mol. employed in this work was 3-mercapto-1-propanesulfonate (MPS). The electrochem. behaviors of various plating formulas were characterized using a galvanostatic measurement on a Cu electrode at different rotating speeds. The MPS adlayer is transferable onto the surface of the Cu deposit and can be displaced by the PEG-Cl-leveler. The displacement rate depends on the mol. structure of the added leveler. This plating process has the potential to greatly reduce the plating time of microvia filling. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Electric Literature of 4569-86-2

The Article related to copper electroplating microvia filling thiol modified seed layer, various leveler copper electroplating thiol modified seed layer, Electrochemistry: Industrial Cathodic Processes and other aspects.Electric Literature of 4569-86-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On January 28, 2022, Zhang, Yong; Lai, Guowei; Nie, Longjun; Lu, Dongliang; Fan, Xiaolin published a patent.Application In Synthesis of 2-Chloro-4-methyl-1-nitrobenzene The title of the patent was Difluorobenzyl reagent, its preparation method and application. And the patent contained the following:

The difluorobenzyl reagent has chem. structural formula I or II shown in claim 1, wherein R is R1 substituted Ph, etc.; R1 is H, etc.; Ar is R2 substituted 4-nitrobenzyl, etc.; R2 is H, etc. The difluorobenzyl reagent is 2-(2,4-dinitrophenyl)-2,2-difluoro-1-phenylethanone, etc. The preparation method includes performing first nucleophilic addition of 2,4-dinitrotoluene and aldehyde under condition of first catalyst (1,8-diazabicyclo[5.4.0]undec-7-ene, etc.) to obtain first nucleophilic structure, reacting with first oxidant (2-iodoxybenzoic acid, etc.) to obtain first oxidation structure, mixing with first selective fluorine reagent (1-chloromethyl-4-fluoro-1,4-diazabicyclo[2,2,2]octane bis(tetrafluoroborate) salt) and first additive (potassium phosphate, etc.), and performing first fluorination to obtain compound I. The preparation method further includes performing second nucleophilic addition reaction of nitro-substituted toluene and benzaldehyde under condition of second additive (1,8-diazabicyclo[5.4.0]undec-7-ene, etc.) to obtain second nucleophilic structure, reacting with second oxidant (2-iodoxybenzoic acid, etc.) to obtain second oxidation structure, mixing with second selective fluorine reagent (1-chloromethyl-4-fluoro-1,4-diazabicyclo[2,2,2]octane bis(tetrafluoroborate) salt) and third additive (potassium phosphate, etc.), and performing second fluorination to obtain compound II. The invention has potential medicinal value. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Application In Synthesis of 2-Chloro-4-methyl-1-nitrobenzene

The Article related to difluorobenzyl preparation application, Aliphatic Compounds: Nitro and Nitroso Compounds and other aspects.Application In Synthesis of 2-Chloro-4-methyl-1-nitrobenzene

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On May 2, 1996, Signor, Angelo; Guerrato, Alfredo; Signor, Giovanni published a patent.Category: chlorides-buliding-blocks The title of the patent was Preparation of furosemide. And the patent contained the following:

Furosemide (I), known diuretic and antihypertensive agent (no data), was prepared by photochlorination of 4-chloro-2-fluoro-toluene followed by aminosulfonylation of 4-chloro-2-fluoro-benzotrichloride and condensation of 4-chloro-2-fluoro-5-(aminosulfonyl)benzoic acid with furfurylamine. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Category: chlorides-buliding-blocks

The Article related to furosemide preparation diuretic antihypertensive, Heterocyclic Compounds (One Hetero Atom): Furans and other aspects.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 28, 1994, Cook, A. Gilbert; Tolliver, Randi M.; Williams, Janelle E. published an article.Category: chlorides-buliding-blocks The title of the article was The blue bottle experiment revisited. How Blue? How Sweet?. And the article contained the following:

The “Blue Bottle” experiment was first popularized by Campbell. The reaction consists of a flask about half full of a colorless liquid that, when shaken, turns blue. When left to stand the liquid turns colorless again. The cyclic process – being shaken, turning blue, being left to stand, and turning colorless – can be repeated many times. By making a series of guided observations with this simple but colorful system, the student can determine a rate law and a plausible mechanism for the reaction without ever knowing the contents of the flask. The activation energy of the reaction can also be measured by making observations at various temperatures This popular experiment has been carried out by general chem. students at Valparaiso University since 1963 with great success. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Category: chlorides-buliding-blocks

The Article related to oxidation reaction experiment blue bottle glucose, History, Education, and Documentation: Education and other aspects.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics