Month: November 2022

Del Grosso, Alessandro published the artcileRegioselective electrophilic borylation of haloarenes, SDS of cas: 765917-27-9, the publication is Chemical Communications (Cambridge, United Kingdom) (2015), 51(14), 2878-2881, database is CAplus and MEDLINE.

Haloarenes undergo direct borylation using amine : BCl₃ : AlCl₃ in the ratio of 1 : 1 : 2. After esterification the pinacol boronate esters are isolated in good yield with regioselectivity controlled by steric and electronic effects.

Chemical Communications (Cambridge, United Kingdom) published new progress about 765917-27-9. 765917-27-9 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Boronic acid and ester,Benzene,Boronate Esters, name is 2-(4-Chloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, and the molecular formula is C12H15BClFO2, SDS of cas: 765917-27-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Oseland, Elizabeth E. published the artcileSurface patterning of polyacrylamide gel using scanning electrochemical cell microscopy (SECCM), COA of Formula: C19H34ClN, the publication is Chemical Communications (Cambridge, United Kingdom) (2016), 52(64), 9929-9932, database is CAplus and MEDLINE.

Scanning electrochem. cell microscopy is introduced as a new tool for the synthesis and deposition of polymers on SAM-functionalized Au surfaces. The deposition of poly(N-hydroxyethyl acrylamide) is enhanced through the electrochem. generation of activating Cu(I)Cl/Me₆TREN catalyst. Initiation of the polymerization reaction is most likely due to in situ generation of reactive O species following O reduction

Chemical Communications (Cambridge, United Kingdom) published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, COA of Formula: C19H34ClN.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Duman, Osman published the artcileApparent molar volumes and isentropic compressibilities of benzyltrialkylammonium chlorides in water at (293.15, 303.15, 313.15, 323.15, and 333.15)K, Synthetic Route of 23616-79-7, the publication is Journal of Chemical Thermodynamics (2009), 41(8), 911-915, database is CAplus.

Densities and ultrasound speeds of benzyltrialkylammonium chlorides (BTAACls) were measured accurately in aqueous solutions at 5 temperatures (293.15, 303.15, 313.15, 323.15, and 333.15) K. The data were utilized in determining apparent molar volumes, V_Φ, and apparent molar isentropic compressibilities, K_SΦ. Infinite dilution values of these apparent molar quantities, V_Φ and K_SΦ , were determined by extrapolation procedures. Contribution of CH₂ groups, along the alkyl groups of BTAACls, to VΦ and K_SΦ values were derived from plots of these quantities as a function of number of addnl. CH₂ groups in going from benzyltrimethylammonium chloride to benzyltributylammonium chloride. The temperature dependencies of V_Φ and K_SΦ values were examined on the basis of isobaric expansivity. Apparent molar isobaric expansivities at infinite dilution, E⁰_Φ, were obtained from the slopes of V_Φ vs. temperature data. Concentration dependencies of V_Φ and K_SΦ were examined A fair correlation was observed between V_Φ and K⁰_SΦ values of the 3 BTAACls.

Journal of Chemical Thermodynamics published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Synthetic Route of 23616-79-7.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Duman, Osman published the artcileAdsorptive removal of cationic surfactants from aqueous solutions onto high-area activated carbon cloth monitored by in situ UV spectroscopy, Recommanded Product: N-Benzyl-N,N-dibutylbutan-1-aminium chloride, the publication is Journal of Hazardous Materials (2010), 174(1-3), 359-367, database is CAplus and MEDLINE.

Activated C cloth (ACC) was used as adsorbent for the removal of cationic surfactants such as benzyltrimethylammonium chloride (BTMACl), benzyltriethylammonium chloride (BTEACl), benzyltributylammonium chloride (BTBACl), benzyldimethyldecylammonium chloride (BDMDACl), benzyldimethyltetradecylammonium chloride (BDMTDACl), benzyldimethylhexadecylammonium chloride (BDMHDACl), N-dodecylpyridinium chloride (N-DPCl) and N-cetylpyridinium chloride (CPCl) from aqueous solutions The adsorption efficiency of the ACC was evaluated for cationic surfactants. Adsorption process was followed by in situ UV spectroscopic technique. The kinetic data, so obtained, were treated according to the pseudo 1st-order, the pseudo 2nd-order, the Elovich and the intraparticle diffusion models in order to understand the adsorption mechanism of cationic surfactants onto the ACC. The best fit was found with the pseudo 2nd-order model. The exptl. isotherm data were obtained at 30° and analyzed by the Freundlich and the Langmuir models. The parameters of isotherm equations were determined The Freundlich model was found to represent the exptl. data better than the Langmuir model. The observed adsorption behaviors are discussed in terms of the pH of the solution, the nature of cationic surfactants (e.g. functional groups, size, and hydrophobicity) and the nature of the ACC (e.g. surface charge, pore size). A fair linear correlation was found between some adsorption parameters and apparent molar volumes at infinite dilution for benzyltrialkylammonium chlorides.

Journal of Hazardous Materials published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Recommanded Product: N-Benzyl-N,N-dibutylbutan-1-aminium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Fujita, Tadashi published the artcileCarnitine. I. Hydrolysis of carnitine nitrile chloride with concentrated hydrochloric acid, Related Products of chlorides-buliding-blocks, the publication is Chemical & Pharmaceutical Bulletin (1961), 661-5, database is CAplus.

The hydrolysis of [Me₃NCH₂CH(OH)CH₂CN]Cl (I) was studied as a possible preparation of carnitine (II), and as a check on the preparation of [Me₃CH₂CH(CH₂CO₂H)O₂CCH₂CH(OH)CH₂NMe₃]2Cl (III) (Dechamps, et al., CA 49, 3816b). I (45 g.) stirred 10 hrs. in an autoclave at 120-30° with 75 cc. concentrated HCl, and the mixture kept overnight at room temperature yielded 83.8% NH₄Cl, from the evaporated filtrate 31 g. crystalline compound (IV), m. 180-90° (decomposition), and from the mother liquor from IV 0.8 g. (Me₃NCH₂CH:CHCO₂H)Cl (V), m. 202-3° (decomposition). Comparison of the infrared spectra of IV, V, and [Me₃NCH₂CH(OH)CH₂CO₂H]Cl (VI) (curves shown) indicated that IV was a mixture of V and VI. To confirm this, 3.6 g. IV was catalytically reduced (PtO₂) in EtOH and yielded 0.2 g. VI, m. 195-6% and 0.6 g. mixture, m. 147-90°, probably VI mixed with (Me₃NCH₂CH₂-CH₂CO₂H)Cl. IV (25 g.) was also separated by fractional crystallization with 95% EtOH into 4.6 g. V and 1.5 g. VI. VI (19.8 g.) hydrolyzed as was I yielded 7.6 g.V. Modifying the hydrolysis of I by stirring only 4 hrs. on a boiling water bath suppressed the formation of V and yielded 85% pure VI. Thus, III could not be detected as a hydrolysis product of I. Salts of II were reported: sulfamate, m. 1478°; eyclohexanesulfamate, m. 121-2°; sulfate, m. 156-7°; nitrate, m. 79-81°; orotate, m. 191°.

Chemical & Pharmaceutical Bulletin published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C7H16ClNO2, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Litvinenko, E. I. published the artcileDynamic and physicomechanical properties of acrylic oxide polymer filled with surface-modified aluminosilicate, Product Details of C38H74Cl2N2O4, the publication is Plasticheskie Massy (2004), 19-20, database is CAplus.

Mech. properties of polymethacrylic dental filling composition based on Me methacrylate-Bu methacrylate copolymer and monomeric Me methacrylate and epoxy-methacrylate adduct filled with aluminosilicate surface-modified with decamethoxine (fungicide) and spasmolytin (spasmolytic) was studied.

Plasticheskie Massy published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Product Details of C38H74Cl2N2O4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Smith, Brandi Patrice published the artcileIdentification of early liver toxicity gene biomarkers using comparative supervised machine learning, Category: chlorides-buliding-blocks, the publication is Scientific Reports (2020), 10(1), 19128, database is CAplus and MEDLINE.

Screening agrochems. and pharmaceuticals for potential liver toxicity is required for regulatory approval and is an expensive and time-consuming process. The identification and utilization of early exposure gene signatures and robust predictive models in regulatory toxicity testing has the potential to reduce time and costs substantially. In this study, comparative supervised machine learning approaches were applied to the rat liver TG-GATEs dataset to develop feature selection and predictive testing. We identified ten gene biomarkers using three different feature selection methods that predicted liver necrosis with high specificity and selectivity in an independent validation dataset from the Microarray Quality Control (MAQC)-II study. Nine of the ten genes that were selected with the supervised methods are involved in metabolism and detoxification (Car3, Crat, Cyp39a1, Dcd, Lbp, Scly, Slc23a1, and Tkfc) and transcriptional regulation (Ablim3). Several of these genes are also implicated in liver carcinogenesis, including Crat, Car3 and Slc23a1. Our biomarker gene signature provides high statistical accuracy and a manageable number of genes to study as indicators to potentially accelerate toxicity testing based on their ability to induce liver necrosis and, eventually, liver cancer.

Scientific Reports published new progress about 637-07-0. 637-07-0 belongs to chlorides-buliding-blocks, auxiliary class Inhibitor,Cell Cycle,PPAR, name is Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate, and the molecular formula is C6H17NO3Si, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Huntress, Ernest H. published the artcileIdentification of organic compounds. IV. Chlorosulfonic acid as a reagent for identification of alkylbenzenes, Recommanded Product: 5,6,7,8-Tetrahydronaphthalene-2-sulfonyl chloride, the publication is Journal of the American Chemical Society (1941), 3446-8, database is CAplus.

cf. C. A. 34, 2804.4. The use of ClSO₃H has been extended to 37 aromatic hydrocarbons. The process of part I (C. A. 34, 2803.9) was used except that 5 mL. of ClSO₃H was used and the reaction product was stirred 45 min. before pouring it onto ice; the chloride was converted by solid (NH₄)₂CO₃ to the amide. The structures of the amides of the monoalkylated benzenes were established by KMnO₄ oxidation of the side chain and indicated that the chlorosulfonylation occurred in the p-position to the side chain. For the polyalkylated benzenes the structures were inferred from previous work. The derivative of C₆H₆, the derivative of the benzenesulfonamide, the m. p. and yield are given. C₆H₆, PhSO₂NH₂, 150-50.5° 23%; Me, 4-Me, 135.5-6°, 36-44%; Et, 4-Et, 109-10° 73-95%; 1,2-Me₂, 3,4-Me₂, 143-4°, 67%; 1,3-Me₂, 2,4-Me₂, 136.5-7° 78%; 1,4-Me₃, 2,5-Me₂, 145.5-6°, 84%; Pr, 4-Pr, 107-8°, 65-95%; iso-Pr, 4-iso-Pr, 104.5-5.5°, 82-8%; 1,2,4-Me₃, 2,4,5-Me₃, 175-6°, 52%; 1,3,5-Me₃, 2,4,6-Me₃, 141.5-2.5°, 57%; Bu, 4-Bu, 94.5-5°, 80%; sec-Bu, 4-sec-Bu, 81-2.5°, 63-72%; tert-Bu, 4-tert-Bu, 136-7°, 100%; iso-Bu, 4-iso-Bu, 84-5°, 82%; 1,4-Me(iso-Pr), 2,5-Me(iso-Pr), 114.5-15.5°, 84-7%; 1,3-Et₂, 2,4-Et₂(?), 98-9°, 57-8%; 1,3,4-Me₂Et, 2,4,5-Me₂Et(?), 147-8°, 80-5%; 1,2,3,4-Me₄, 2,3,4,5-Me₄, 183.5-4°, 85%; 1,2,3,5-Me₄, 2,3,4,6-Me₄, 141.5-2°, 82%; 1,2,4,5-Me₄, 2,3,5,6-Me₄, 153-4°, Am, 4-Am, 85.5-6.5°, 80-100%; tert-Am, 4-tert-Am, 83-4°, 89-90%; 1,3,4-Me₂Pr, 2,4,5-Me₂Pr(?), 90-3°, 79-82%; 1,3,4-Me₂(iso-Pr), 2,4,5-Me₂(iso-Pr)(?), 155.5-6°, 68%; 1,3,5,2-Me₃Et, 2,4,6,3-Me₃Et, 131-2°, 64-71%; Me₅, Me₅, 182-3° 90-2%; hexyl, 4-hexyl, 85-5.5°, 81%; 1,3,4-Me₂(tert-Bu), gives an amide m. 128-30° (81%); 1,3,5-Me₂(tert-Bu), 2,4,6-Me₂(tert-Bu)(?), 132-3°, 86%; 1,3,5-Et₃, 2,4,6-Et₃, 118-18.5°, 94%; 1,4-di-tert-Bu, 2,5-di-tert-Bu, 135.5-6.5°, -; nonyl, 4-nonyl, 94.5-5° 54-67%; hendecyl, 4-hendecyl, 95.7-6.2°, ; cyclohexyl, 4-cyclohexyl, 160-60.5°, 85-7%; 1,2,4,5-tetra(iso-Pr), 2,3,5,6-tetra-iso-Pr, 154.5-5° 60-85%. The following 1-benzenesulfonyl chlorides were isolated: 4-Me, 64-6°, 61-5%; 3,4-Me₂, 52°, 74-86%; 2,4,6-Me₃, 50-3°, 65-72%; 4-tert-Bu, 80-2°, 100%; 2,3,4,5-Me₄, 72-3°, 95%; 2,3,5,6-Me₄, 98-9°, 100%; Me₅ 77-8.5°, 98%; 2,4,6-Me₂(tert-Bu), 65-7°, 97%; 4-cyclohexyl, 51-2.5°; 2,3,5,6-tetra(iso-Pr), 141.5-42°, 77-86%. The amount of sulfone formation was considerable (27%) only in the case of C₆H₆; PhMe gives 1-10%, PhEt 1-6%, iso-PrPh 2-3%, but the other hydrocarbons gave no evidence of corresponding products. Hydrindene gives 65-70% of the 5-sulfonamide, m. 132.5-3.5°; 1,2,3,4-tetrahydronaphthalene gives 75% of 5,6,7,8-tetrahydro-2-naphthalenesulfonamide, m. 134.5-5°; the sulfonyl chloride m. 58-8.5°.

Journal of the American Chemical Society published new progress about 61551-49-3. 61551-49-3 belongs to chlorides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 5,6,7,8-Tetrahydronaphthalene-2-sulfonyl chloride, and the molecular formula is C10H11ClO2S, Recommanded Product: 5,6,7,8-Tetrahydronaphthalene-2-sulfonyl chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Rosin, Hadassa published the artcileAddition of trichloromethane phosphonyldichloride and its derivatives to vinylic monomers and other olefins, SDS of cas: 866-23-9, the publication is Journal of Organic Chemistry (1975), 40(22), 3298-9, database is CAplus.

Trichloromethanephosphonyl dichloride adds to vinylic monomers and other olefins under iron or copper chloride catalysis by a redox chain mechanism, giving RCH(Cl)CH2CCl2POCl2. Under forcing conditions, ethylene adds to its own monoadduct to give (ClCH2CH2)2CClPOCl2. Diphenyl trichloromethanephosphonate reacts in the same fashion, but with the dimethyl and diethyl ester the addition stops far short of completion.

Journal of Organic Chemistry published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, SDS of cas: 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Patil, Vrushali published the artcileBiological evaluation of some synthesized benzothiazole derivatives and their characterization, Application In Synthesis of 3696-23-9, the publication is World Journal of Pharmaceutical Research (2015), 4(2), 842-850, database is CAplus.

Synthesis, characterization and biol. evaluation of [(1,3-benzothiazol-2-yl)-3,3-phenyl-1H-pyrazol-4-yl]methylidene thioureas I [R = H, 4-HO, 4-Cl, 4-C₂H₅O, 3,5-(MeO)₂] was reported. The compounds containing benzothiazole nucleus were treated with hydrazine hydrate to form hydrazone derivative followed by reaction with acetophenone and further cyclization via Vilsmeier-Haack reaction using DMF/POCl₃ and thus obtained intermediates were finally condensed with substituted thiourea. The structure of compounds I were confirmed by spectral anal. such as FT-IR, NMR, mass spectrophotometer and were further screened for various in-vitro biol. activities such as anti-oxidant, anti-inflammatory, anti-microbial activities. It was found that compounds I showed enhancing biol. activity.

World Journal of Pharmaceutical Research published new progress about 3696-23-9. 3696-23-9 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Thiourea,Amine,Benzene,Amide, name is 1-(4-Chlorophenyl)thiourea, and the molecular formula is C7H7ClN2S, Application In Synthesis of 3696-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics