Facile Regioselective Synthesis of Novel bis-Thiazole Derivatives and Their Antimicrobial Activity was written by Mahmoodi, Nosrat O.;Parvizi, Jafar;Sharifzadeh, Bahman;Rassa, Mehdi. And the article was included in Archiv der Pharmazie (Weinheim, Germany) in 2013.Recommanded Product: 1-Bromo-6-chlorohexane The following contents are mentioned in the article:
The design and synthesis of several new bis[thiazole] derivatives serving as bis[drug] dimers in comparison with mono-heterocyclic analogs are described. These bis-drugs present superior medicinal and pharmacol. activities against both Gram-neg. (Pseudomonas aeruginosa and Escherichia coli) and Gram-pos. (Micrococcus luteus and Bacillus subtilis) bacteria, which are in general more sensitive to compounds with higher hydrophobicity. Compounds with higher hydrophobicity exhibited some activity against Gram-neg. bacteria. The synthesis of the target compounds was achieved by a cyclization of thiourea with (phenyl)ethanone dimer derivatives The title compounds thus formed included a thiazolamine dimer compound (I) and related substances. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Recommanded Product: 1-Bromo-6-chlorohexane).
1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Recommanded Product: 1-Bromo-6-chlorohexane
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics