A gold(I)-catalyzed intramolecular tandem cyclization reaction of alkylidenecyclopropane-containing alkynes was written by Fang, Wei;Wei, Yin;Shi, Min. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2017.Application of 1186603-47-3 The following contents are mentioned in the article:
A novel gold(I)-catalyzed intramol. tandem cyclization reaction of ortho-(arylethynyl)arenemethylenecyclopropanes 2-X-4-R1-5-R2C6H2CCY [X = cyclopropylidenemethyl, 2-methylprop-1-en-1-yl, cyclobutylidenemethyl, etc.; Y = C6H5, thiophen-2-yl, 3,4,5-(OCH3)3C6H2, etc.; R1 = H, Me, F, Cl; R2 = Me, F, NO2, Cl, CF3; R1, R2 = -OCH2O-] provided an efficient approach to prepare functionalized 11H-benzo[a]fluorene derivatives e.g., I in moderate to good yields. Further transformations as well as applications of the products have been presented and a plausible reaction mechanism has also been proposed on the basis of deuterium labeling and control experiments This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Application of 1186603-47-3).
5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Application of 1186603-47-3
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics