Novel hydrophobic deep eutectic solvents for ultrasound-assisted dispersive liquid-liquid microextraction of trace non-steroidal anti-inflammatory drugs in water and milk samples was written by Qiao, Lizhen;Sun, Ruiting;Yu, Chunmei;Tao, Yuan;Yan, Yang. And the article was included in Microchemical Journal in 2021.Safety of N-Methyl-N,N-dioctyloctan-1-aminium chloride The following contents are mentioned in the article:
In the present study, several novel and natural hydrophobic deep eutectic solvents (HDESs) were prepared, and one of the HDESs composed of guanidinium chloride and thymol was advantageously used to develop an ultrasound-assisted dispersive liquid-liquid microextraction (UA-DLLME) method combined with high-performance liquid chromatog. for the determination of four non-steroidal anti-inflammatory drugs (NSAIDs). Several important parameters influencing extraction efficiency were investigated and optimized, including the type and volume of HDES, ultrasound time, solution pH and the amount of salt addition Under optimal exptl. conditions, the method showed good linearity with the determination coefficients (R2) of 0.994-0.999 in the linear range of 5-2000μg/L, low limits of detection of 0.5-1μg/L and acceptable recoveries in the range of 79.42%-107.52%. The proposed method was successfully applied for the pretreatment of trace NSAIDs in real water and milk samples, and the results demonstrated the potential of the synthesized HDES for the extraction and determination of contaminants in aqueous samples. This study involved multiple reactions and reactants, such as N-Methyl-N,N-dioctyloctan-1-aminium chloride (cas: 5137-55-3Safety of N-Methyl-N,N-dioctyloctan-1-aminium chloride).
N-Methyl-N,N-dioctyloctan-1-aminium chloride (cas: 5137-55-3) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Safety of N-Methyl-N,N-dioctyloctan-1-aminium chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics