Wilson, Danielle published the artcileTurning “On” and “Off” a Pyridoxal 5′-Phosphate Mimic Using Light, Product Details of C15H14Cl2S2, the publication is Angewandte Chemie, International Edition (2012), 51(22), 5431-5434, S5431/1-S5431/13, database is CAplus and MEDLINE.
The use of light to reversibly change the structure of biol. relevant mols., thereby turning important biochem. functions “on” and “off” on command, offers a non-invasive, rapid, spatial and temporal tool for research and therapy. The biol. active form of vitamin B6 is pyridoxal 5′-phosphate (PLP), a versatile enzyme cofactor responsible for amino acid metabolism in all organisms from bacteria to humans. The present work describes the development of a photoresponsive PLP mimic whose catalytic activity can be reversibly switched “on” and “off” by irradiating it with UV and visible light, resp. This was accomplished by taking advantage of the photoswitchable dithienylethene (DTE) architecture, which undergoes UV light-dependent ring-closing and visible light-dependent ring-opening reactions. The ability of this photoresponsive PLP mimic to serve as a controllable catalyst was demonstrated using hydrogen-deuterium exchange experiments and 1H NMR spectroscopy of solutions of optically pure
Angewandte Chemie, International Edition published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H12O8, Product Details of C15H14Cl2S2.
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https://en.wikipedia.org/wiki/Chloride,
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