Felton, Lloyd C.’s team published research in Science (Washington, DC, United States) in 105 | CAS: 19652-33-6

Science (Washington, DC, United States) published new progress about 19652-33-6. 19652-33-6 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Bromide,Benzene,Phenol,Aldehyde, name is 5-Bromo-3-chloro-2-hydroxybenzaldehyde, and the molecular formula is C7H4BrClO2, Category: chlorides-buliding-blocks.

Felton, Lloyd C. published the artcileAction of substituted salicylaldehydes on bacteria and fungi, Category: chlorides-buliding-blocks, the publication is Science (Washington, DC, United States) (1947), 409-10, database is CAplus and MEDLINE.

The following 8 substituted derivatives of salicylaldehyde (I) were tested for antibacterial and fungi-static activity: 5-Cl-I, 5-Br-I, 5-I-I, 5-tert-butyl-I, 3,5-di-Cl-I, 3,5-di-Br-I, 3-Cl-5-Br-I, and 3-Br-5-tert-butyl-I. All of these compounds completely inhibited the growth of Trichophyton metagraphytes on agar plates when present in a 5% concentration, and some were active for the fungus as low as 0.005%. Both gram-neg. (Shigella and Pseudomonas sp.) and gram-pos. (Staphylococcus and Streptococcus sp.) bacteria were inhibited by dilutions of 1:500 to 1:64,000 of the various compounds 3,5-Dibromo-I (trade name Dalyde) is being studied more extensively both in vitro and in vivo against pathogenic bacteria and fungi.

Science (Washington, DC, United States) published new progress about 19652-33-6. 19652-33-6 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Bromide,Benzene,Phenol,Aldehyde, name is 5-Bromo-3-chloro-2-hydroxybenzaldehyde, and the molecular formula is C7H4BrClO2, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics