Chance, Leon H. published the artcile2,4-Diaminotrihalopropyltriazines derived from γ-trihalobutyronitriles, Category: chlorides-buliding-blocks, the main research area is trichlorobutyronitrile; butyronitrile trihalo; triazinediamine trihalopropyl; butyrate trihalo cyclization biguanide; biguanidine cyclization trihalobutyrate.
Cl3CCH2CH2CN and Br3CCH2CH2CN were prepared in improved yields by modification of reported methods by reacting the appropriate haloform with H2C:CHCN. Cl3CCH2CH2CO2Me, Cl3CCH2CH2CO2Et, Br3CCH2CH2CO2Me and Br3CCH2CH2CO2Et were prepared from the corresponding nitriles. 2,4-Diamino-6-(3,3,3-trichloro-1-propyl)-1,3,5-triazine and 2,4-diamino-6-(3,3,3-tribromo-1-propyl)-1,3,5-triazine were prepared by the reaction of the corresponding methyl or ethyl trihalobutyrates with biguanide. The tetramethylol derivatives of the triazines, viz., 2,4-bis[di(hydroxymethyl)amino]-6-(3,3,3-trichloro-1-propyl)-1,3,5-triazine and 2,4-bis[di(hydroxymethyl)amino]-6-(3,3,3-tribromo-1-propyl)-1,3,5-triazine, were prepared by the reaction of the triazines with alk. aqueous formaldehyde.
Journal of Chemical and Engineering Data published new progress about Cyclocondensation reaction. 19376-57-9 belongs to class chlorides-buliding-blocks, name is Methyl 4,4,4-trichlorobutanoate, and the molecular formula is C5H7Cl3O2, Category: chlorides-buliding-blocks.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics