Sone, Toshihiko; Yamaguchi, Akitake; Matsunaga, Shigeki; Shibasaki, Masakatsu published an article in 2012, the title of the article was Enantioselective synthesis of 2,2-disubstituted terminal epoxides via catalytic asymmetric Corey-Chaykovsky epoxidation of ketones.Related Products of 5034-06-0 And the article contains the following content:
Catalytic asym. Corey-Chaykovsky epoxidation of various ketones RCOR1 (R = Ph, 1-naphthyl, n-octyl, etc., R1 = Me; R = Ph, 4-ClC6H4, 3-pyridyl, etc., R1 = ET, n-Pr, CHMe2) with dimethyloxosulfonium methylide using a heterobimetallic La-Li3-BINOL complex (LLB) is described. The reaction proceeded smoothly at room temperature in the presence of achiral phosphine oxide additives, and 2,2-disubstituted terminal epoxides I were obtained in high enantioselectivity (97%-91% ee) and yield (>99%-88%) from a broad range of Me ketones with 1-5 mol% catalyst loading. Enantioselectivity was strongly dependent on the steric hindrance, and other ketones, such as Et ketones and Pr ketones resulted in slightly lower enantioselectivity (88%-67% ee). The experimental process involved the reaction of trimethyloxosulphonium chloride(cas: 5034-06-0).Related Products of 5034-06-0
The Article related to enantioselective synthesis terminal epoxide asym corey chaykovsky epoxidation ketone, epoxide enantioselective synthesis corey chaykovsky epoxidation ketone, Heterocyclic Compounds (One Hetero Atom): Ethylene Oxides and other aspects.Related Products of 5034-06-0
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics