On November 5, 2010, Peixoto, Sabrina; Nguyen, Tuan Minh; Crich, David; Delpech, Bernard; Marazano, Christian published an article.Computed Properties of 14602-86-9 The title of the article was One-Pot Formation of Piperidine- and Pyrrolidine-Substituted Pyridinium Salts via Addition of 5-Alkylaminopenta-2,4-dienals to N-Acyliminium Ions: Application to the Synthesis of (±)-Nicotine and Analogs. And the article contained the following:
Addition of 5-alkylaminopenta-2,4-dienals onto N-acyliminium ions, generated in situ from α-hydroxycarbamates derived from pyrrolidine or piperidine, in the presence of zinc triflate, followed by dehydrative cyclization, allowed the formation of pyridinium salts substituted at their 3-position by a five- or six-membered nitrogen heterocycle. Subsequent N-dealkylation of the pyridinium moiety and deprotection of the secondary amine or reduction of the carbamate function led to (±)-nicotine and analogs. The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).Computed Properties of 14602-86-9
The Article related to nitrogen heterocycle preparation addition cyclization alkylaminopetadienal hydroxycarbamae, nicotine analog synthesis, Alkaloids: Alkaloids Containing Two Nitrogen Atoms and other aspects.Computed Properties of 14602-86-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics