On December 12, 2000, Kudo, Koji; Suemoto, Takahiro; Suzuki, Masako; Tojo, Hitomi; Shimazu, Hiroshi published a patent.HPLC of Formula: 4569-86-2 The title of the patent was Azure A analogs as imaging agents and probes for diagnosis of diseases related to amyloid accumulation. And the patent contained the following:
Azure A analogs (I; R1, R4 = H, halogen, C1-4 alkyl; R2, R3 = H, halogen, amino, C1-4 alkyl-substituted amino, etc.; R5, R6 = H, halogen C1-4 alkyl etc.; R7, R8 = H, halogen, C1-4 alkyl; R9 = H, halogen, amino, C1-4 alkyl-substituted amino; X = CH, N; Y = NH, S, etc.; Z = anion) and their radioactive (11C, 13N, 15O, or 18F)-labeled compounds, including Acridine Orange, Acridine Orange HCl, BF 009, Neutral Red, and Methylene Blue, and their salts are claimed as imaging agents and probes for diagnosis of diseases related to amyloid accumulation. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).HPLC of Formula: 4569-86-2
The Article related to azure a analog imaging agent amyloid, Radiation Biochemistry: Disease Diagnosis and Therapy and other aspects.HPLC of Formula: 4569-86-2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics