On March 12, 2021, Wang, Kai; Jia, Fang; Song, Shihao; Zhao, Fang; Pan, Jie; Zhao, Yimei; Jiang, Jun; Ye, Wenjing published a patent.Reference of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride The title of the patent was Preparation of methylene violet derivatives as fluorescent probes for sulfide ion detection. And the patent contained the following:
The title compounds with general formula I•Cl- [wherein R1 = -NHCOCH2-R3, -NH(CH2O)n-R3, –NH(CH2NH)n-R3, -NH(CH2)n-R3, -N=N-(p-phenyl)-R3 or R3, where R3 is 7-nitro-4-(1-piperazinyl-4-yl)-2,1,3-benzoxadiazole; R2 = NH2 or N(Et)2; n = independently 1-12] were prepared as fluorescent probes. For example, compound II•Cl- was prepared in a multi-step synthesis. The fluorescent probe can be used for sulfide ion detection or preparing photodynamic therapy probe. The invention has good water solubility, high detection sensitivity, simple synthesis, mild condition, and low cost. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Reference of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride
The Article related to preparation methylene violet derivative fluorescent probes sulfide ion detection, Heterocyclic Compounds (More Than One Hetero Atom): Pyridazines, Cinnolines, and Phthalazines and other aspects.Reference of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics