On August 1, 2012, Wang, Kai; Song, Lvhua; Chen, Yunfeng; Yu, Faquan; Chi, Ruan; Huang, Ting published a patent.Application In Synthesis of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride The title of the patent was Synthesis of janus green B. And the patent contained the following:
The method comprises dissolving 4-amino-N,N-diethyl aniline in an aqueous acid , mixing with aniline at molar ratio of 1: 1-2 in the presence of inorganic oxidants (chromate, permanganate, or peroxo acid salt), stirring at pH 4-7, -5 to 50°C for 0.5-5 h, reacting with 1-2 M fold aniline, reacting at 0-100°C for 1-10 h, filtering, vacuum concentrating, precipitating, filtering, drying cake to obtain methylene purple 3RAX, adding into acid water at -5°C, slowly dripping sodium nitrite aqueous solution, reacting at -5 to 25°C for 1-5 h, reacting with 1-2 M fold N,N-didimethylaniline for 1-10 h, vacuum distilling, dispersing residue in saturated saline, filtering, and drying cake. This invention has easy-obtained raw materials, simple process, and certain industrialization value. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Application In Synthesis of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride
The Article related to janus green b dye synthesis, Dyes, Organic Pigments, Fluorescent Brighteners, and Photographic Sensitizers: Heterocyclics and other aspects.Application In Synthesis of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics