Peng, Haixia; Chen, Xuxing; Chen, Yanhong; He, Qian; Xie, Yuyuan; Yang, Chunhao published an article in 2011, the title of the article was Solvent-free synthesis of δ-carbolines/carbazoles from 3-nitro-2-phenylpyridines/2-nitrobiphenyl derivatives using DPPE as a reducing agent.Application In Synthesis of 2-Chloro-4-methyl-1-nitrobenzene And the article contains the following content:
A green and efficient preparation of functionalized δ-carbolines/carbazoles via reductive ring closure by 1,2-bis(diphenylphosphino)ethane under solvent-free conditions is described. The starting materials 3-nitro-2-phenylpyridines/2-nitrobiphenyl derivatives are readily prepared through Suzuki-Miyaura cross-coupling reaction from com. available compounds And the polar byproduct ethane-1,2-diylbis(diphenylphosphine oxide) is easily removed from the relatively polar reaction mixture Various substituted δ-carbolines/carbazoles are obtained in acceptable yields. It is particularly worth mentioning that substrates with electron-withdrawing groups (EWG) also give the desired products in good yield. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Application In Synthesis of 2-Chloro-4-methyl-1-nitrobenzene
The Article related to carboline preparation, carbazole preparation, nitro phenyl pyridine preparation, reductive ring closure nitro phenylpyridine nitrobiphenyl dppe, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Application In Synthesis of 2-Chloro-4-methyl-1-nitrobenzene
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics