On November 30, 2021, Leite, Irena; Andrianov, Victor; Zelencova-Gopejenko, Diana; Loza, Einars; Kazhoka-Lapsa, Iveta; Domracheva, Ilona; Stoyak, Marta; Chlopicki, Stefan; Kalvins, Ivars published an article.Reference of Methyl 6-chloro-6-oxohexanoate The title of the article was Aziridine-2-carboxylic acid derivatives and its open-ring isomers as a novel PDIA1 inhibitors. And the article contained the following:
Acyl derivatives of aziridine-2-carboxylic acid have been synthesized and tested as PDIA1 inhibitors. Calculations of charge value and distribution in aziridine ring system and some alkylating agents were performed. For the first time was found that acyl derivatives of aziridine-2-carboxylic acid are weak to moderately active PDIA1 inhibitors. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Reference of Methyl 6-chloro-6-oxohexanoate
The Article related to aziridine carboxylic acid preparation pdia1 inhibitor, Heterocyclic Compounds (One Hetero Atom): Ethylene Sulfides and Other 3-Membered Rings and other aspects.Reference of Methyl 6-chloro-6-oxohexanoate
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics