On November 7, 2017, Fu, Zhengjiang; Cai, Hu; Li, Zhaojie; Jiang, Ligao published a patent.SDS of cas: 38939-88-7 The title of the patent was Method for synthesizing aryl halide from aryl carboxylic acid as raw material. And the patent contained the following:
The invention relates to a method for synthesizing aryl halide from aryl carboxylic acid as raw material. The method prepares corresponding aryl halide from an aryl carboxylic acid compound and halide MX through substitution reaction in a solvent and in the presence of oxygen, silver catalyst, copper additive and a bidentate nitrogen ligand, wherein M in MX is alkali metal or alk. earth metal, and X is F, Cl, Br or I. Compared with the conventional aryl halide synthesis method, the method has the obvious advantages such as easily available low-cost reaction raw materials including aryl carboxylic acid and MX, small consumption of metal catalyst, little environmental pollution, good tolerance to multiple functional groups on aromatic ring, and high yield. The method can be widely applied to synthesis of drugs, materials and natural products in the industrial field and academia. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).SDS of cas: 38939-88-7
The Article related to arylhalide preparation substitution, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.SDS of cas: 38939-88-7
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics