On September 11, 2009, Botton, Gerard; Valeur, Eric; Kergoat, Micheline; Charon, Christine; Elbawab, Samer published a patent.SDS of cas: 38939-88-7 The title of the patent was Preparation of quinoxalinone derivatives as insulin secretion stimulators useful for the treatment of diabetes. And the patent contained the following:
The title compounds I [R1 = H, alkyl, cycloalkyl, aryl, etc.; R6 = alkyl, aryl, heteroaryl, etc.; R2-R5 = H, Y or Z; Y = alkyl, cycloalkyl, heterocycloalkyl, etc.; Z = OH, SH, halo, CN. etc.], useful as insulin secretion stimulators for the prophylaxis and/or treatment of diabetes and pathologies associated, were prepared E.g., a multi-step synthesis of II, starting from 2-chloronitrobenzene and 2,2-difluoroethylamine, was given. Exemplified compounds I were evaluated in pancreatic INS-1 cells for their superior response to glucose (data given for representative compounds I). Pharmacetical composition comprising I is disclosed. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).SDS of cas: 38939-88-7
The Article related to quinoxalinone preparation insulin secretion stimulator antidiabetic, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazines and Quinoxalines (Including Piperazines) and other aspects.SDS of cas: 38939-88-7
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics