On September 30, 1996, Bomben, Andrea; Marques, Carlos A.; Selva, Maurizio; Tundo, Pietro published an article.Category: chlorides-buliding-blocks The title of the article was Synthesis of substituted phenyl ketones via Pd-catalyzed hydrodechlorination of their polychlorinated derivatives. And the article contained the following:
2- And 3-methylacetophenone, 2- and 3-methylbenzophenone, and 2,2′-, 2,3′- and 3,3′-dimethylbenzophenone were prepared through a Pd-catalyzed hydrodechlorination of the corresponding dichlorinated derivatives The reaction was carried out under multiphase conditions at 30-50°, by bubbling H2 at atm. pressure into a biphasic system constituted by isooctane and 50% aq KOH, in the presence of Pd/C and Aliquat 336. Likewise, fluorinated aceto- and benzophenones were prepared starting from the corresponding chlorinated methylfluoro- and dimethylfluoro ketones. The presence of the onium salt allows the reaction to proceed with a high chemoselectivity. Cl is moved while both the reduction of the carbonyl group and/or fluorine removal are prevented. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Category: chlorides-buliding-blocks
The Article related to phenyl ketone preparation, palladium catalyzed hydrodechlorination chlorophenyl ketone, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ketones and Derivatives, Including Quinones and Sulfur Analogs and other aspects.Category: chlorides-buliding-blocks
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics