On November 21, 2012, Yu, Juntian; Zhang, Ling; Sun, Zhiguo; Luan, Xiuli published a patent.Quality Control of 4-Chloro-2-fluorotoluene The title of the patent was Method for preparing 4-chloro-2-fluorotoluene. And the patent contained the following:
The invention relates to the method for preparation of 4-chloro-2-fluorotoluene. 4-Chloro-2-fluorotoluene was prepared via salt formation of 5-chloro-2-methylaniline with hydrofluoric acid; the resulting 5-chloro-2-methylaniline hydrofluoric acid salt underwent diazotization to give 5-chloro-2-methylphenyldiazonium fluoride, which underwent denitrogenation to give the title compound The method has few steps, high yield and high product purity. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Quality Control of 4-Chloro-2-fluorotoluene
The Article related to chloro methyl aniline salt formation, hydrofluoric acid salt chloro methyl aniline preparation diazotization, phenyl diazonium fluoride preparation denitrogenation, fluoro methyl toluene preparation and other aspects.Quality Control of 4-Chloro-2-fluorotoluene
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics