Wei, Hao-Zhao; Yu, Liu-Zhu; Shi, Min published an article in 2020, the title of the article was Lewis or Bronsted acid-catalysed reaction of propargylic alcohol-tethered alkylidenecyclopropanes with indoles and pyrroles for the preparation of polycyclic compounds tethered with indole or pyrrole motif.Product Details of 89-77-0 And the article contains the following content:
A facile synthetic method to access cyclopenta[b]naphthalene derivatives I (R1 = H, 3-Me, 5-Me, 4-CF3, 5-OMe, 4-MeO, 4-Cl; R2 = Ph, 4-MeOC6H4, 3-thienyl; R3 = H, Me, OMe, Cl, F; R4 = H, Me, OMe, Cl; R5 = N-methylpyrrol-2-yl, indol-3-yl, N-phenylindol-3-yl, etc.) via the Lewis or Bronsted acid catalyzed cascade nucleophilic addition, electronic cyclization, ring-opening rearrangement of propargylic alc.-tethered alkylidenecyclopropanes II (R6 = H, 5-MeO, 5-Cl, 6-Me, etc.) with indole and pyrrole derivatives was developed. The reaction exhibited a broad substrate scope and good functional group tolerance under metal-free conditions, affording the desired products in moderate to good yields. The experimental process involved the reaction of 2-Amino-4-chlorobenzoic acid(cas: 89-77-0).Product Details of 89-77-0
The Article related to cyclopenta naphthalene indole preparation, propargylic alc alkylidenecyclopropane indole cyclization lewis acid catalyst, naphthalene cyclopenta pyrrole preparation, pyrrole propargylic alc alkylidenecyclopropane cyclization lewis acid catalyst and other aspects.Product Details of 89-77-0
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Chloride – Wikipedia,
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