Sharma, Sushila; Kumar, Manoranjan; Sharma, Shruti; Nayal, Onkar S.; Kumar, Neeraj; Singh, Bikram; Sharma, Upendra published an article in 2016, the title of the article was Microwave assisted synthesis of phenanthridinones and dihydrophenanthridines by vasicine/KOtBu promoted intramolecular C-H arylation.Quality Control of 2-Chloro-4-nitrobenzoic acid And the article contains the following content:
A simple, efficient, rapid and transition metal-free methodol. has been developed by utilizing vasicine (a natural product), as a catalyst for the synthesis of phenanthridinones and dihydrophenanthridines. The reaction proceeds through intramol. C-H arylation with aryl halides in the presence of KOtBu as a base under microwave irradiation in sulfolane as a solvent. The reaction proceeds well with various aryl iodides, bromides and more remarkably with less reactive aryl chlorides for 15 min, providing the corresponding products in 45-90% yields. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Quality Control of 2-Chloro-4-nitrobenzoic acid
The Article related to phenanthridinone hydrophenanthridine synthesis vasicine potassium butoxide intramol arylation microwave, aryl halide intramol arylation phenanthridinone hydrophenanthridine synthesis and other aspects.Quality Control of 2-Chloro-4-nitrobenzoic acid
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