On October 5, 2020, Ryabchuk, Pavel; Leischner, Thomas; Kreyenschulte, Carsten; Spannenberg, Anke; Junge, Kathrin; Beller, Matthias published an article.Product Details of 99-60-5 The title of the article was Cascade Synthesis of Pyrroles from Nitroarenes with Benign Reductants Using a Heterogeneous Cobalt Catalyst. And the article contained the following:
A bifunctional 3d-metal catalyst for the cascade synthesis of diverse pyrroles from nitroarenes is presented. The optimal catalytic system Co/NGr-C@SiO2-L is obtained by pyrolysis of a cobalt-impregnated composite followed by subsequent selective leaching. In the presence of this material, (transfer) hydrogenation of easily available nitroarenes and subsequent Paal-Knorr/Clauson-Kass condensation provides >40 pyrroles in good to high yields using dihydrogen, formic acid, or a CO/H2O mixture (WGSR conditions) as reductant. In addition to the favorable step economy, this straightforward domino process does not require any solvents or external co-catalysts. The general synthetic utility of this methodol. was demonstrated on a variety of functionalized substrates including the preparation of biol. active and pharmaceutically relevant compounds, for example, (+)-Isamoltane. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Product Details of 99-60-5
The Article related to pyrrole preparation cascade reaction, nitroarenes hydrogenation paal knorr clauson kass condensation supported co, cobalt, heterogeneous catalysis, hydrogenation, nitroarene, pyrrole and other aspects.Product Details of 99-60-5
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics