On November 15, 2013, Romero-Estudillo, Ivan; Boto, Alicia published an article.Synthetic Route of 14602-86-9 The title of the article was Creating diversity by site-selective peptide modification: A customizable unit affords amino acids with high optical purity. And the article contained the following:
The development of peptide libraries by site-selective modification of a few parent peptides would save valuable time and materials in discovery processes, but still is a difficult synthetic challenge. Herein natural hydroxyproline is introduced as a “convertible” unit for the production of a variety of optically pure amino acids, including expensive N-alkyl amino acids, and to achieve the mild, efficient, and site-selective modification of peptides. The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).Synthetic Route of 14602-86-9
The Article related to hydroxyproline amino acid regioselective synthesis tandem radical scission oxidation, oxo homoalanine reductive amination lactamization horner wadsworth emmons reaction, peptide synthesis hydroxyproline reduction alkylation and other aspects.Synthetic Route of 14602-86-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics