On July 20, 2020, Plaza, Manuel; Jandl, Christian; Bach, Thorsten published an article.COA of Formula: C7H11ClO3 The title of the article was Photochemical Deracemization of Allenes and Subsequent Chirality Transfer. And the article contained the following:
Trisubstituted allenes with a 3-(1′-alkenylidene)-pyrrolidin-2-one motif were successfully deracemized (13 examples, 86-98% ee) employing visible light (λ=420 nm) and a chiral triplet sensitizer as the catalyst (2.5 mol %). The photocatalyst likely operates by selective recognition of one allene enantiomer via hydrogen bonds and by a triplet-sensitized racemization process. Even a tetrasubstituted allene (45% ee) and a seven-membered 3-(1′-alkenylidene)-azepan-2-one (62% ee) could be enantiomerically enriched under the chosen conditions. It was shown that the axial chirality of the allenes can be converted into point chirality by a Diels-Alder (94-97% ee) or a bromination reaction (91% ee). Ring opening of the five-membered pyrrolidin-2-one was achieved without significantly compromising the integrity of the chirality axis (92% ee). The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).COA of Formula: C7H11ClO3
The Article related to allene deracemization chiral resolution chiral triplet sensitizer enantioselectivity light, chiral trisubstituted allene preparation, allenes, chiral resolution, enantioselectivity, hydrogen bonds, photochemistry, sensitizers and other aspects.COA of Formula: C7H11ClO3
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics