Li, Bowen; Li, Tiejun; Aliyu, Muinat A.; Li, Zhen Hua; Tang, Wenjun published an article in 2019, the title of the article was Enantioselective Palladium-Catalyzed Cross-Coupling of α-Bromo Carboxamides and Aryl Boronic Acids.Electric Literature of 98946-18-0 And the article contains the following content:
We herein report an enantioselective palladium-catalyzed cross-coupling between α-bromo carboxamides and aryl boronic acids, generating a series of chiral α-aryl carboxamides in good yields and excellent enantioselectivities. The development of a chiral P,P=O ligand was critical in overcoming the second transmetalation issue and allows the first asym. palladium-catalyzed coupling of α-bromo carbonyl compounds The experimental process involved the reaction of tert-Butyl trichloroacetimidate(cas: 98946-18-0).Electric Literature of 98946-18-0
The Article related to enantioselective alpha aryl carboxamide preparation palladium catalyst, cross coupling alpha bromo carboxamide arylboronic acid phosphorus ligand, asymmetric catalysis, cross-coupling, palladium, phosphorus ligands, transmetalation and other aspects.Electric Literature of 98946-18-0
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics