On August 3, 2021, Joshi, Bhaskar D.; Chisholm, John D. published an article.SDS of cas: 98946-18-0 The title of the article was Formation of pyrroloindolines via the alkylation of tryptamines with trichloroacetimidates. And the article contained the following:
Pyrroloindolines and related systems are present in a large number of complex natural products. These core structures have generated considerable synthetic interest, as many of the compounds possess challenging, elaborate structures and interesting biol. properties. Recently, we have focused on using trichloroacetimidates for the synthesis of these fascinating mols., e.g., I. Trichloroacetimidates can be used as an electrophilic source of an alkyl group to form the pyrroloindoline directly from tryptamine derivatives In this manner trichloroacetimidates provide a flexible solution to forming highly functionalized pyrroloindoline core structures, needing only a catalytic amount of a Lewis acid to effect the requisite transformations. The experimental process involved the reaction of tert-Butyl trichloroacetimidate(cas: 98946-18-0).SDS of cas: 98946-18-0
The Article related to pyrroloindoline preparation electrophilic alkylation cyclization tryptamine trichloroacetimidate, alkylation, heterocycle, pyrroloindoline, trichloroacetimidate, tryptamine and other aspects.SDS of cas: 98946-18-0
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics