On December 31, 2015, Hu, Peng; Bach, Thorsten published an article.SDS of cas: 35444-44-1 The title of the article was Synthesis of Alkyl-Substituted Pyridines by Directed Pd(II)-Catalyzed C-H Activation of Alkanoic Amides. And the article contained the following:
A general alkylation protocol for substituted iodopyridines was developed, e.g., I, (32 examples, 44-97% yield). The reaction is based on the Pd(II)-catalyzed C-H activation of 8-aminoquinoline-derived alkanoic amides and it employs a catalyst cocktail of Pd(OAc)2 (10 mol%), NaI (30 mol%), and (BuO)2POOH (20 mol%), with Ag2CO3 as base. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).SDS of cas: 35444-44-1
The Article related to alkyl pyridine aminoquinoline alkanoic amide preparation, infractin preparation, dihydrocanthinone preparation, iodo carboline alkylation, aminoquinoline alkanoic amide iodopyridine alkylation palladium catalyst and other aspects.SDS of cas: 35444-44-1
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics