Engl, Oliver D.; Saadi, Jakub; Cosimi, Elena; Wennemers, Helma published an article in 2017, the title of the article was Synthesis of Monothiomalonates – Versatile Thioester Enolate Equivalents for C-C Bond Formations.Recommanded Product: tert-Butyl trichloroacetimidate And the article contains the following content:
A method for the preparation of monothiomalonates, used as thioester enolate equivalent for stereoselective C-C bond formation, is disclosed; the method allows the thioester and ester groups and the carbon substituents to be varied. Reaction of Meldrum’s acid and 2-substituted Meldrum’s acids with arylthiols or (4-methoxyphenylthio)trimethylsilane mediated by Et3N and TMSCl in MeCN yielded malonic acid monothioesters which were isolated in most cases by extraction O-alkylation of the resulting malonic acid monothioesters with alkyl triflates or alkyl acetimidates yielded the desired monothiomalonates in 34-92% overall yields. The experimental process involved the reaction of tert-Butyl trichloroacetimidate(cas: 98946-18-0).Recommanded Product: tert-Butyl trichloroacetimidate
The Article related to monothiomalonate preparation, ring opening meldrum acid aryl thiol chlorotrimethylsilane ethylamine, alkylation malonic acid monothioester alkyl trichloroacetimidate triflate and other aspects.Recommanded Product: tert-Butyl trichloroacetimidate
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics