Chloride substituents modify the physical properties of organic compounds in several ways. 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Application In Synthesis of 104-86-9.
Tadros, Joseph;Dankers, Christian;Jurisinec, Ashley;Menti-Platten, Maria;Aldrich-Wright, Janice R.;Gordon, Christopher P. research published 《 A Comparison of Immobilised Triphenylphosphine and 1-Hydroxybenzotriazole as Mediators of Catch-and-Release Acylation Under Flow Conditions》, the research content is summarized as follows. Herein, a comparative study of immobilized triphenylphosphine (PS-PPh3) and 1-hydroxybenzotriazole (PS-HOBt) to mediate amide couplings under continuous flow was described. Compared to Appel-type amidations (PS-PPh3), the developed ‘catch-and-release’ approach (PS-HOBt) afforded near-quant. amide conversions. Utilizing this strategy, sulfonyl chloride amenability enabled facile access to an expanded library of sulfonate and sulfonamides. Post-constructional peptide modification was also demonstrated, affording two Nβ-functionalized pentapeptides in high yields and purities. In contrast to frequently utilized coupling agents, the PS-HOBt resin could be recycled six times without a reduction in efficacy or regeneration requirements.
104-86-9, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., Application In Synthesis of 104-86-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics