Chloride substituents modify the physical properties of organic compounds in several ways. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Synthetic Route of 6334-18-5.
Sorkhabi, Serve;Mozafari, Roya;Ghadermazi, Mohammad research published 《 New advances in catalytic performance of erbium-folic acid-coated CoFe2O4 complexes for green one-pot three-component synthesis of pyrano[2,3-d]pyrimidinone and dihydropyrano[3,2-c]chromenes compounds in water》, the research content is summarized as follows. Herein, the green synthesis magnetic nanoparticles (MNPs) of cobalt ferrite by the immobilization of erbium (Er) coated with folic acid (FA) was reported which showed effective catalytic properties and recyclability. Full characterizations with field emission SEM (FE-SEM), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDX), X-ray at. mapping, thermal gravimetric anal. (TGA), X-ray diffraction (XRD), vibrating sample magnetometer (VSM), inductively coupled plasma-optical emission spectrometry (ICP-OES), and Fourier-transform IR (FT-IR) spectroscopy techniques were undertaken to uncover structural properties of the prepared magnetic catalyst. The obtained nanohybrid complexes as efficient, recyclable, and green heterogeneous systems pave the way for producing pyrano[2,3-d]pyrimidinone I [R = H, 4-Me, 3-OMe, etc.] and dihydropyrano[3,2-c]chromenes derivatives II [R1 = 4-Me, 4-F, 2-Cl, etc.] by the one-pot three-component condensation reaction of various aldehydes, malononitrile, and hydroxycoumarin or barbituric acid in green condition. This easily prepared organometalic catalyst presented many superiorities such as operational simplicity, high yield, short reaction time, utilization of com. available or easily accessible starting materials, eco-friendly properties, and excellent purity. Most importantly, erbium-FA-coated CoFe2O4 could be easily separated and recycled from the reaction system using an external magnetic field. The magnetically recoverable biocatalyst can be recycled and reused six times while maintaining high activities. The activity of the magnetic catalyst could be maintained at more than 80% of that of the previous cycle. This research solved the recovery problem encountered in industrial applications of biocatalysts and presents a clean and green method for preparing pyrimidinones and chromenes.
6334-18-5, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., Synthetic Route of 6334-18-5
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics