Chlorinated organic compounds are found in nearly every class of biomolecules. 1878-65-5, formula is C8H7ClO2, Name is 3-Chlorophenylacetic acid. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Name: 3-Chlorophenylacetic acid.
Smith, Samuel M.;Greenhalgh, Mark D.;Feoktistova, Taisiia;Walden, Daniel M.;Taylor, James E.;Cordes, David B.;Slawin, Alexandra M. Z.;Cheong, Paul Ha-Yeon;Smith, Andrew D. research published 《 Scope, Limitations and Mechanistic Analysis of the HyperBTM-Catalyzed Acylative Kinetic Resolution of Tertiary Heterocyclic Alcohols》, the research content is summarized as follows. The full scope and limitations of the catalytic acylative kinetic resolution of a range of tertiary heterocyclic alcs. (78 examples, s up to >200) is reported under operationally-simple conditions, using low loadings of a com. available Lewis basic isothiourea catalyst, HyperBTM (generally 1 mol %). The protocol is highly effective for the kinetic resolution of 3-substituted 3-hydroxyoxindole and α-substituted α-hydroxylactam derivatives bearing up to three potential recognition motifs at the stereogenic tertiary carbinol center. The full power of this methodol. has been showcased through the synthesis of highly enantioenriched biol.-active target compounds in both enantiomeric forms. To provide further insight into the reaction mechanism, a detailed kinetic anal. of this Lewis base-catalyzed acylation of tertiary alcs. is reported using the variable time normalization anal. (VTNA) method.
1878-65-5, 3-Chlorophenylacetic acid is a useful research compound. Its molecular formula is C8H7ClO2 and its molecular weight is 170.59 g/mol. The purity is usually 95%.
3-Chlorophenyl acetic acid is a compound that has resonance mass of 269. The compound reacts with HBr and water to produce 3-chlorobenzene, carbon dioxide and hydrogen chloride. A reaction product of this chemical is covid-19 pandemic (a type of drug)., Name: 3-Chlorophenylacetic acid
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics